A vehicle caught fire and burned early Wednesday after it was hit by an 18-wheeler on the side of Interstate 49.

One person is dead and another injured after a pickup truck driving the wrong way on Interstate 49 crashed into an 18-wheeler ...

It happened just before the Red Bridge exit - a car hit a man rolling east to west across southbound I-49 for reasons unknown ...

CRAWFORD COUNTY, Ark. (KNWA/KFTA) — Traffic on Interstate 49 northbound in Crawford County is moving slowly after a vehicle ...

The Natchitoches Parish Sheriff's deputies, Louisiana State Police, Natchitoches Regional Medical Center EMS, and ...

Louisiana State Police Troop I was called to investigate a two-vehicle fatality crash on Interstate 49 about three miles ...

A Pineville man died Sunday after a two-vehicle wreck on Interstate 49 in Natchitoches Parish, according to Louisiana State ...

Love’s Travel Stops is growing its network along Interstate 49 in Missouri with the addition of a new travel stop in Jasper, ...