49ers, Bills and San Francisco

Major 49ers injury update unfortunately might be coming too late
The sky is falling in the Bay Area, but the San Francisco 49ers finally got some good and 'potentially significant' news. Per NFL Network's Ian Rapoport, San F
Bills vs. 49ers injury update: San Francisco could be without four Pro Bowlers
San Francisco played without four key players - quarterback Brock Purdy, left tackle Trent Williams, defensive end Nick Bosa and cornerback Charvarius Ward - and was clobbered 38-10 by the Green Bay Packers on Sunday.
San Francisco 49ers vs Buffalo Bills picks, predictions, odds: Who wins NFL Week 13 game?
NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco 49ers and Buffalo Bills.
First look: San Francisco 49ers at Buffalo Bills odds and lines
The San Francisco 49ers (5-6) take on the Buffalo Bills (9-2) on Sunday Night Football in Week 13. Kickoff from Highmark Stadium is set for 8:20 p.m. ET (NBC). Below, we look at 49ers vs. Bills odds from BetMGM Sportsbook's NFL odds before making our expert NFL picks and predictions later in the week.
Buffalo Bills' week is already off to an interesting start thanks to latest injury update
Buffalo is coming out of their bye week ready and willing to tackle the playoff push, with their eyes set on a higher target. The AFC East hasn't been clinched yet, but with six games to play, Buffalo already has a potential hat and t-shirt game on the docket for Sunday Night Football when they host the San Francisco 49ers.
2025 Super Bowl odds: Steelers suffer significant drop, Lions the favorite
How have Super Bowl odds changed over the last week? Let's take a look at the most recent sports betting odds for Super Bowl ...
The Spun on MSN2d
San Francisco 49ers Saddened By Death Of 3-Time Super Bowl Champion
The San Francisco 49ers are mourning the loss of a three-time Super Bowl champion. One of the best defensive linemen in San ...
Rolling Out16h
Brock Purdy and the 49ers are done; Why it’s time to blow the team up
The 49ers have always been "better together." Take one key player away, they look weaker. Take two players away, they look ...
49ers Super Bowl Champion Suddenly Dies at 80
San Francisco 49ers three-time Super Bowl champion has suddenly passed away at 80, the team announced on Thursday.
NBC Sports Regional: Bay Area on MSN15h
Woody emphatically puts real, giant fork in 49ers' Super Bowl hopes
The 49ers are taking a beating Monday, a day after the Green Bay Packers blew them out of Lambeau Field. San Francisco now ...
Colin Cowherd's honest take on 'old, tired' 49ers team' after loss to Packers
Following their loss in Week 12 to the Packers, Colin Cowherd stirred the pot, giving his honest take on an 'old, aging' ...
Fox Sports2d
2024-25 San Francisco 49ers Odds: Odds to win Super Bowl, NFL Playoffs, Division
As of Nov. 24 the San Francisco 49ers' odds of winning the Super Bowl, +3500, put them 11th in the NFL. The 49ers were defeated by the Seattle Seahawks 20-17 in their most recent game.
San Francisco 49ers’ George Kittle On How Team Can Get Over Super Bowl Hump And Details His Cool Partnership With Zenni Optical
San Francisco 49ers tight end George Kittle has two objectives for this season — remain healthy and win a Super Bowl.
Josh Allen One 'Scary' Trait Turning Heads in Bills Super Bowl Push
Buffalo Bills quarterback Josh Allen is leading his team in a way he hasn't done in years prior, and it's a worry for the ...