The NFL is just about as unpredictable as the Buffalo weather at this time of the year, so the 49ers will take their ...

San Francisco 49ers quarterback Brock Purdy is expected to return Sunday against the Buffalo Bills, head coach Kyle Shanahan ...

The San Francisco 49ers could have Brock Purdy back soon, as the quarterback was recently seen throwing passes in a video ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

But even when most or all of those Niners took the field this year, closing out games has been a glaring weakness for a team expected to compete for the NFC. A loss to Seattle in Week 11 marked the ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night ...

San Francisco 49ers quarterback Brandon Allen could get a second consecutive start filling in for starter Brock Purdy (shoulder) when the 49ers play at the Buffalo Bills on Sunday night. Head coach ...

Los Angeles Chargers (7-4) at Atlanta Falcons (6-5), 1 p.m. ET, FOXAtlanta holds a one-game lead over the Tampa Bay ...

Who should I start for Week 13? Fantasy football outlooks for Jauan Jennings, Bucky Irving, Khalil Shakir. Our expert fantasy ...

Following their high-profile victory over the AFC-leading Chiefs, the Bills went off the NFL radar for their much-needed Week ...

In this game, the Packers defense faced an offense that was missing Brock Purdy due to a shoulder injury and elbow soreness ...