Christian McCaffrey is deadly serious about his 9-to-5 job — head coach Kyle Shanahan calls him “a psycho in the best way ...

The San Francisco 49ers are up against the Buffalo Bills in Week 13. The 49ers have dealt with an array of injuries this ...

The San Francisco 49ers didn’t have many changes to their Thursday practice participation report.

San Francisco 49ers head coach Kyle Shanahan was strong in defending Christian McCaffrey from criticism following his poor ...

Providing the betting odds and our preview and prediction for the star-studded matchup between the San Francisco 49ers and ...

Christian McCaffrey is averaging a mere 3.5 yards per carry this season since he returned from bilateral Achilles tendonitis. Here's what McCaffrey said about h ...

For the second successive day, Brock Purdy was listed as limited in San Francisco 49ers practice with the shoulder injury ...

But even when most or all of those Niners took the field this year, closing out games has been a glaring weakness for a team expected to compete for the NFC. A loss to Seattle in Week 11 marked the ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

The 49ers’ situation could grow even more dire if Brock Purdy isn’t ready for Sunday’s must-win matchup against the Buffalo ...

In a season where running backs are thriving in the NFL, the 49ers hope to get Christian McCaffrey back on track.