San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

Lake effect snow is slamming the Great Lakes, with seven states from Wisconsin to New York under snow alerts on Monday.

Bills quarterback Josh Allen and head coach Sean McDermott celebrated by making snow angels after Buffalo clinched its fifth ...

Parts of the Great Lakes region saw new snow Monday and faced the prospect of even more this week after U.S. travelers ...

State and team officials brought all hands on deck to ensure that a massive dose of lake effect snow would not hinder Buffalo ...

Tonight the Buffalo Bills will proceed with playing the San Francisco 49ers at 8:20 p.m. Orchard Park already had 22.9 inches ...

Allen scored a traditional rushing touchdown early in the fourth quarter, giving him three touchdowns on two plays in the ...

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

San Francisco fumbled the ball three times and lost all three. Brock Purdy dropped back to pass 20 times for 86 net yards.

The swagger is officially gone from this season's 49ers after another miserable outing in a 35-10 loss in Buffalo.

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...