San Francisco coach Kyle Shanahan told reporters postgame that their star running back had injured the posterior cruciate ...

The Buffalo Bills are now slightly favored over the Kansas City Chiefs to finish as the No. 1 seed in the AFC.

"GMFB" on what do you make of the Buffalo Bills Week 13 "Sunday Night Football" win vs. the San Francisco 49ers.

In eight season’s San Francisco 49ers tight end George Kittle never played in Buffalo at Highmark Stadium. Despite the loss ...

During the San Francisco 49ers 35-10 loss to the Buffalo Bills on Sunday night, superstar running back Christian McCaffrey ...

Let’s have a look at the state of the NFC West, what happened in Week 13 and what is coming up in Week 14 The Seahawks won ...

San Francisco 49ers quarterback Brock Purdy feels sorry for the brutal injury suffered by Christian McCaffrey.

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

The 49ers' disappointing season took another negative turn in their Week 13 loss to the Bills, and George Kittle addressed ...

Christian McCaffrey’s injury threatens to sideline the 49ers’ star running back for the rest of the season. The team’s ...

The San Francisco 49ers suffered another crushing defeat, this time in a snowy showdown against the Buffalo Bills. The 35-10 ...

Mike Florio and Chris Simms recap the 49ers loss to the Bills on SNF, including Christian McCaffrey's injury in the first ...