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49ers RB's season may be over

San Francisco 49ers RB Christian McCaffrey injures knee in second quarter

Christian McCaffrey is dealing with another long-term injury again. The San Francisco 49ers running back went down with a knee injury during the second quarter of the team's "Sunday Night Football Game" loss to the Buffalo Bills and never returned.

ABC7 San Francisco · 6m

49ers RB Christian McCaffrey injures PCL in loss to Bills

RB Christian McCaffrey, playing in just his fourth game since returning from Achilles tendinitis, suffered a PCL injury Sunday night in Buffalo that coach Kyle Shanahan described as potentially season-ending.

SFGATE on MSN · 54m

49ers fear Christian McCaffrey suffered season-ending PCL injury

The worst fears for the San Francisco 49ers and star Christian McCaffrey may have been realized, as the star running back did not return to Sunday’s snowy game in Buffalo after exiting with a non-contact injury.

49ers, Bills and NFL

Yahoo! Sports · 46m

49ers make ugly NFL history with blowout losses to Packers, Bills

The San Francisco 49ers' losses to the Green Bay Packers and Buffalo Bills mark the worst two-game stretch by a defending conference champion since the 1970 merger.

Newsweek on MSN · 7h

How to Watch 49ers vs Bills: Live Stream NFL, TV Channel

The San Francisco 49ers make the trip to snowy Buffalo, NY to face Josh Allen and the Buffalo Bills on Sunday Night Football.

CBS SF Bay Area on MSN · 2h

49ers lose 35-10 to Josh Allen, Bills for third straight loss

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills clinched their fifth straight AFC East title with a 35-10 victory over the San Francisco 49ers on a snowy Sunday night.

NBC Sports Regional: Bay Area on MSN1h

Where 49ers would pick in 2025 NFL Draft if season ended today

Here's where the 49ers sit in the 2025 NFL Draft order after San Francisco's 35-10 blowout loss to the Buffalo Bills on ...

Bills vs. 49ers live updates: NFL scores, game stats, news, highlights, where to watch 'Sunday Night Football'

We're live with the Week 13 edition of "Sunday Night Football" as the Buffalo Bills play host to the San Francisco 49ers to ...

1hon MSN

Bills ice out 49ers in Week 13 drubbing as Josh Allen cements NFL MVP case

A picturesque setting of snow was the perfect backdrop for a Buffalo Bills team that has now won its fifth straight AFC East ...

7hon MSN

San Francisco 49ers at Buffalo Bills: Predictions, picks and odds for NFL Week 13 game

Watch out for the tables on "Sunday Night Football." The nightcap of Sunday's action will be in northern New York with the ...

San Francisco 49ers 10-35 Buffalo Bills: Josh Allen the star as Bills cruise to fifth straight AFC East title

The Buffalo Bills clinched another AFC East title with a dominant 35-10 win over the San Francisco 49ers; Josh Allen had ...

Winners, losers as Bills rout depleted 49ers 35-10 on Sunday Night Football

The Buffalo Bills easily got past the San Francisco 49ers 35-10 on a snowy Sunday Night Football matchup. Here are winners ...

What channel is Bills vs 49ers on tonight? Time, TV schedule for NFL Sunday Night Football

The 2024 NFL Week 13 games end with Sunday Night Football as the Buffalo Bills host the San Francisco 49ers. NFL TV schedule, ...

'Sunday Night Football' highlights: Bills dominate 49ers 35-10 for 7th straight win, claim AFC East

The 49ers look to turn around their season with a win in Buffalo against the Bills, who are chasing the top seed in the AFC.

Sporting News21h

Will 49ers fire Kyle Shanahan? Why San Francisco coach isn't on hot seat despite disappointing season

Shanahan is in his eighth season as head coach of the 49ers. He was hired by San Francisco in February 2017, shortly after his stint as Falcons offensive coordinator ended in a humiliating Super Bowl ...

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49ers RB's season may be over

49ers, Bills and NFL

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