Former Wisconsin running back Isaac Guerendo scored the second touchdown of his young NFL career in the San Francisco 49ers’ ...

State and team officials brought all hands on deck to ensure that a massive dose of lake effect snow would not hinder Buffalo ...

The 49ers (5-7) are alone in last place in the NFC West for the first time since the 2020 season ended. On the heels of this ...

SportsLine's model has simulated San Francisco vs. Buffalo on Sunday Night Football 10,000 times and revealed its SNF picks ...

The 2024 NFL Week 13 games end with Sunday Night Football as the Buffalo Bills host the San Francisco 49ers. NFL TV schedule, ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

We're live with the Week 13 edition of "Sunday Night Football" as the Buffalo Bills play host to the San Francisco 49ers to ...

The Bills will look to resume its path to the No. 1 seed in the AFC with MVP front runner Josh Allen leading the charge. ...

The 49ers look to turn around their season with a win in Buffalo against the Bills, who are chasing the top seed in the AFC.

The San Francisco 49ers are reeling. They've lost two straight games to fall to 5-6 and under .500 for the fourth time this ...

Although Coleman and Kincaid are out, Buffalo will welcome one offensive starter back to the lineup. Right tackle Spencer ...

The San Francisco 49ers are visiting the Buffalo Bills, and they’re getting some December Buffalo weather. The Buffalo team ...