Samuel pulled in four of his five targets for 20 yards with a lost fumble in Sunday's 35=10 loss to the Bills.

San Francisco 49ers wide receiver Deebo Samuel Sr. didn't do much to regain fantasy managers' confidence during a 35-10 defeat to the Bills in Buffalo on Sunday night. Samuel Sr. finished with four ...

As for the Week 13 Sunday slate, no game is bigger than the showdown between the Philadelphia Eagles and Baltimore Ravens ...

The 49ers are 0-3 ATS in their last three games. The Bills are 5-1 ATS in their last six games with five of those six games ...

Brandon Allen is 2-8 in 10 career starts. One of them was against Josh Allen and the Bills but Brandon Allen wore No. 2 in ...

Buffalo Bills wide receiver Jalen Virgil pounces on San Francisco 49ers wide receiver Deebo Samuel's fumble as the Bills' ...

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...

San Francisco 49ers wide receiver Deebo Samuel once again showcases his kick return prowess on a 42-yard return.

Deebo Samuel speaks to reporters after San Francisco’s 35-10 loss to the Buffalo Bills on Sunday at Highmark Stadium.Deebo ...

The Bills sacked Purdy twice, Greg Rousseau getting one while the other was called a team sack because Purdy lost a fumble ...

Ahead of their game against the Buffalo Bills, it’s time to release our San Francisco 49ers Week 13 predictions.

10:47 p.m.: Allen's night is done. Mitchell Trubisky is heading into the contest. Allen's final line: 13-of-17 passing for ...