The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

Christian McCaffrey pulled up limping after taking a pitch early in their game against the Bills on Sunday night.

The weather outside was frightful at Highmark Stadium in Orchard Park, New York on Sunday night, but the way the San ...

Crews used plows to clear Highmark Stadium walkways, and the parking lots surrounding the stadium were cleared and salted ...

One week after a 38-10 road loss to the Green Bay Packers that stood out as one of their ugliest defeats in years, the San ...

This weekend brought Western New York’s first major lake-effect snow event of the season. The heaviest snow totals through ...

Officials in upstate New York counties have declared a state of emergency as they prepare for a major snowstorm that has ...

The 49ers had three fumbles in Sunday night's contest, all three of which were recovered by the Bills. San Francisco's ...

One week after a 38-10 road loss to the Green Bay Packers that stood out as one of their ugliest defeats in years, the San Francisco 49ers put on a performance against the Buffalo Bills at Highmark ...

Christian McCaffrey will not return to Sunday's matchup against the Bills. McCaffrey has been downgraded to out with the knee ...

The 49ers were absolutely shellacked Sunday for a second straight week as the Buffalo Bills beat them 35-10 on national ...

The Buffalo Bills embrace the elements, possibly more than any other team in the NFL. Sure, the Packers and Steelers turn out ...