San Francisco 49ers quarterback and Iowa State alum Brock Purdy is showing promising signs after being injured on Nov. 17.

Getting blown out at Green Bay following another squandered late lead the previous week against Seattle has quickly turned ...

San Francisco's interior offensive line was comfortably second best as the 49ers slumped to a 38-10 loss at Lambeau Field, ...

The 49ers keep losing key players to injuries. The latest one who could miss time is rookie right guard Dominick Puni. He ...

San Francisco has put up a combined 27 points the past two weeks and faces a Bills defense great at generating pressure with ...

Sure, if your fantasy team is 10-2 (or even 9-3), you can relax a little — you’re almost certainly headed to the playoffs. But even then, there’s still the matter of securing a first-round bye — ...

That led to a disappointing 4-6 week for me in predicting the top 10 defense, only hitting on Houston, Denver, Tampa Bay, and Philadelphia. We’ll try to right the ship in Week 13 with a lot of ...

The Los Angeles Rams are still in thick of the division race despite a brutal loss on Sunday night. The tightest division ...

The Bills return from their bye week with a tough test on Sunday Night Football. Here's a look ahead to the matchup.

Next up for Bills, 9-2, are the beleaguered San Francisco 49ers, 5-6, who limp into Highmark Stadium on Sunday night riding a ...

San Francisco quarterback Brock Purdy took part in some light throwing on Monday after missing his first career game because ...

How have Super Bowl odds changed over the last week? Let's take a look at the most recent sports betting odds for Super Bowl ...