The Buffalo Bills are fresh off of their bye week heading into a Sunday Night Football matchup with the San Francisco 49ers, ...

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco ...

San Francisco played without four key players - quarterback Brock Purdy, left tackle Trent Williams, defensive end Nick Bosa ...

San Francisco 49ers head coach Kyle Shanahan told reporters that quarterback Brock Purdy did some light throwing without any ...

The San Francisco 49ers and Buffalo Bills will clash on "Sunday Night Football." Here's how to watch the Week 13 NFL game ...

Here’s how you can watch, stream and listen to the game. Bills vs. 49ers will air on NBC. Mike Tirico will be on play-by-play ...

The 49ers have been careful not to open practice windows for any of their players too early. With that in mind, if everything ...

This Sean McDermott stat should give Buffalo Bills fans confidence entering their Week 13 matchup with the San Francisco ...

The San Francisco 49ers are playing Brandon Allen at quarterback in Week 12 against the Green Bay Packers. The team’s ...

The San Francisco 49ers are optimistic about the status of quarterback Brock Purdy for their Week 13 clash with the Buffalo ...

Two words can sum up the Week 12 matchup between the visiting San Francisco 49ers and the host Green Bay Packers: utter ...

Take a look at the 16 games on the Week 13 NFL schedule this week, starting with three games on Thanksgiving ( Chicago Bears ...