The San Francisco 49ers received some brutal news on Sunday evening. According to head coach Kyle Shanahan, running back ...

RB Christian McCaffrey, playing in just his fourth game since returning from Achilles tendinitis, suffered a PCL injury ...

McCaffrey limped off the field and straight into the injury tent after the play, and was seen heading to the locker room accompanied by trainers shortly after. The team provided an update indicating ...

San Francisco 49ers running back Christian McCaffrey left Sunday night's contest versus the Buffalo Bills with what the team ...

ORCHARD PARK, N.Y. (WROC) — In wintry conditions at Highmark Stadium, the Bills took down the 49ers 35-10 to win their fifth ...

San Francisco 49ers running back Christian McCaffrey suffered another injury in just his fourth game of the season. During ...

Josh Allen became the first quarterback since 1970 to score a rushing touchdown, pass for a touchdown and have a scoring ...

Buffalo was a perfect 4-for-4 in the red zone. A big factor in the Bills' success was their run game. RB James Cook had 14 ...

McCaffrey left Sunday’s blowout loss in Buffalo with a knee injury, and Kyle Shanahan was quick to rule him out.

Facing their seventh loss of the season, 49ers HC Kyle Shanahan gave an update on RB Christian McCaffrey who left the game ...

On a night when Josh Allen threw a touchdown pass and scored one on the same play, the strangest sight on the snowy field at ...

San Francisco 49ers running back Christian McCaffrey's season might be over after he suffered a PCL injury on "Sunday Night ...