The Buffalo Bills (9-2) will try to build on a six-game winning streak when they host the San Francisco 49ers (5-6) on Sunday ...

The San Francisco Standard, that city’s lively and well-funded digital upstart, is experimenting with tiered membership.

The Sunday after Thanksgiving is traditionally the busiest travel day nationally. International, Oakland International and ...

On World Aids Day Sunday, there was a commemoration at the National AIDS Memorial Grove in San Francisco's Golden Gate Park.

Christian McCaffrey was having a resurgent game against the Buffalo Bills. He finally looked like the player who was supposed ...

The San Francisco 49ers received some brutal news on Sunday evening. According to head coach Kyle Shanahan, running back Christian McCaffrey suffered a potentially season-ending PCL injury in their 35 ...

How thorough was the Buffalo Bills’ 35-10 win over the San Francisco 49ers on Sunday night? Quarterback Josh Allen was ...

The 49ers take on the Bills on "Sunday Night Football" in Week 13. Here's the latest on if QB Brock Purdy will be available ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

Rescuers pulled 18 people from the San Francisco Bay after a boat carrying a rowing team capsized, California officials ...

After three strong weeks of play from 49ers RB Christian McCaffrey, he left the game against the Bills after suffering a knee ...